Health Condition 1: null- Overt hypothyroidism
Conditions
Interventions
Intervention1: Water-soluble vitamins at 2-10 times RDA given through oral route of administration: Cap Becosules 1 BD for 2 months
Control Intervention1: Placebo given through oral route of administr
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: For Cases - 1. Drug-naïve overt hypothyroidism 2. Treatment with 100µg/day of levothyroxine For Controls- 1. Healthy Euthyroid individuals
Exclusion criteria
Exclusion criteria: 1. Individuals with secondary causes for thyroid dysfunction or other co-existing endocrine or immunological diseases 2. Patients on medications that interfere with thyroid function 3. Patients who have undergone or are undergoing radiotherapy to the head and neck region 4. Smoking and/or alcohol-drinking 5. Diabetes Mellitus 6. Hypertension 7. Pregnancy â?? at the time of enrollment or during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in parameters of oxidative stress, endothelial dysfunction and inflammation in intervention groupTimepoint: 1 month and 2 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in side-effects observed during treatment in intervention groupTimepoint: 1 month and 2 months | — |
Countries
India
Contacts
Public ContactDr Zachariah Bobby
JIPMER
Outcome results
None listed