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sexual dysfunction and other adverse effects in patients taking atypical antipsychotics

COMPARISON OF THE ADVERSE EFFECT PROFILE OF ATYPICAL ANTIPSYCHOTICS- RISPERIDONE, OLANZAPINE AND QUETIAPINE WITH PARTICULAR EMPHASIS ON SEXUAL DYSFUNCTION

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2014/05/004627
Enrollment
150
Registered
2014-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients on Atypical Antipsychotics

Interventions

None listed

Sponsors

Scandashree K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients of age group 18-60 years who are married. 2. Diagnosed with schizophrenia and other psychotic disorders (ICD-10 F20). 3. Taking any one of the atypical antipsychotic- either resperidone, olanzapine, or quetiapine for at least 4 weeks duration.

Exclusion criteria

Exclusion criteria: 1. Subjects with history of sexual dysfunction prior to antipsychotic intake. 2. Acute or severe psychotic state including delirium, dementia and other cognitive diseases. 3. Chronic medical conditions like DM, h/o stroke, unstable cardiac condition, arrhythmias, substance use disorders and endocrine disorders. 4. Patients who are taking additional medications like mood stabilizers, antidepressants. 5. Patients with sensory impairment. 6. Patients not willing to participate in the study

Design outcomes

Primary

MeasureTime frame
1.To assess the prevalence of sexual dysfunction among patients on atypical antipsychotics- risperidone, olanzapine and quetiapine.Timepoint: 6 months

Secondary

MeasureTime frame
1. To assess whether the occurrence of adverse effects are dose dependent. 2. To assess the frequency of other adverse effects- psychic, neurologic, autonomic, weight changes, reproductive side-effects related to risperidone, olanzapine, quetiapine Timepoint: 6 months

Countries

India

Contacts

Public ContactScandashree K

Father Muller Medical College

padmajaudaykumar@gmail.com9880890512

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026