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To see the effect of differant doses of atracurium in relation to the surgical conditions in paediatric cataract surgery

Evaluation of minimum dose of atracurium in paediatric cataract surgery: a randomised controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/05/004604
Enrollment
160
Registered
2014-05-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patient posted for routine paediatric cataract surgery

Interventions

Intervention1: In group-I,No atracurium will be injected will be injected.: Equal volume of saline will be injected Intervention2: Atracurium will be injected three minutes before insertion of LMA in

Sponsors

Department of Anaesthesiology All India Institute of Medical Sciences New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: This prospective, double blind, randomized controlled trial would be conducted in the Department of Anesthesiology AIIMS, New Delhi after Institute Ethical Committee approval. Patients will than be divided into four groups: In the operating room, standard monitors [electrocardiography (ECG), NIBP, pulse oximetry (SpO2)] will be applied. General anaesthesia will be induced with sevoflurane and oxygen till the loss of eyelash reflex. An intravenous line will be secured followed by injection fentanyl 1µg/kg. An anesthesiologist will then open the envelope to randomize patients into four groups. Group I: Surgery without muscle relaxant Group II: Will receive Atracurium at 25% ED95 Group III: Will receive Atracurium at 50%ED95 Group IV: Will receive Atracurium of 100%ED95

Exclusion criteria

Exclusion criteria: 1. Child with major systemic illness 2. Active upper respiratory tract infection 3. Refusal to participate in the study 4. ASA III and IV 5. Refusal to participate in the study 6. Any neuromuscular disease 7. Children with craniofacial anomalies.

Design outcomes

Primary

MeasureTime frame
1. To see whether muscle relaxant is required or not in paediatric cataract surgery 2. To see the minimum dose of muscle relaxant necessary for cataract surgery. Timepoint: From time of starting inhalation agents till the extubation of LMA.—

Secondary

MeasureTime frame
To see the minimum dose of Atracurium required for paediatric cataract surgeryTimepoint: Induction of anaesthesia to till shifting of patient to recovery room.—

Countries

India

Contacts

Public Contactvanlalnghaka Darlong

All India Institute of Medical Sciences, New Delhi

darlongv@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026