Health Condition 1: null- Age 18 years Primigravida Single gestation Cephalic presentation at â?¥ 36 wk of gestation In early spontaneous labour (cervical dilation â?¤ 5 cm) Baseline pain score 30 (on a 0-100 VAS)
Conditions
Interventions
Intervention1: Steroid group: This group will receive dexamethasone 8mg intravenously diluted to 50 ml with normal saline 45 minutes before insertion of epidural catheter and will receive 10 ml of lev
Sponsors
GMCH chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: • American Society of Anesthesiologists (ASA) grade I and II • Age >18 years • Primigravida • Single gestation • Cephalic presentation at >= 36 wk of gestation • In early spontaneous labour (cervical dilation • Baseline pain score > 30 (on a 0-100 VAS) • Able to use PCEA pump • Requesting epidural analgesia for labour
Exclusion criteria
Exclusion criteria: • Refusal by parturient. • Parturients who had received parenteral opioids in the last 4 hours. • Systemic and local sepsis. • Deranged coagulation profile. • Parturients having multiple pregnancies and premature labour. • Obstetric complications (e.g., premature rupture of amniotic membranes). • Noncephalic presentations. • Allergy to study drugs, i.e. levobupivacaine and fentanyl. • H/O peptic ulcer disease. • Known case of uncontrolled Diabetes Mellitus. • Patient who have received dexamethasone in last 7 days for foetal lung maturity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hourly average consumption of levobupivacaine and fentanyl mixture, including both continuous background infusion plus bolus doses (in ml) corrected for the duration of labour.Timepoint: At the end of delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| Apgar scoreTimepoint: 1 and 5 minute after delivery;Foetal heart rateTimepoint: Continuous foetal heart rate monitoring.;Haemodynamic parameters of motherTimepoint: 5 min for the first 20 min and then every 1 h until delivery;Maternal satisfaction and Pain score (VAS) Timepoint: Every 5 min for the first 20 min and then every 1 h until delivery, on a 0-100 scale.;Sensory and motor block characteristicsTimepoint: Sensory block at midline every 5 min for the first 20 min and then every 1 h until delivery. Lower limb motor block every 5 min using the modified Bromage scale | — |
Countries
India
Contacts
Public ContactDr Pratibha dube
GMCH chandigarh
Outcome results
None listed