Health Condition 1: null- Epithelial carcinoma ovary FIGO stage III and Stage IV post neoadjuvant chemotherapy
Conditions
Interventions
Intervention1: Diagnostic laparoscopy in patient undergoing interval cytoreduction for carcinoma ovary: Validation of laparoscopy based model developed by Faggoti A et al (2006) to predict optimal cy
Sponsors
Regional cancer centre
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient must be under 75 years of age. 2. Patient must have Stage III ovarian cancer by pre operative CT imaging . 3. Patient must have a WHO performance score of 0 â?? 2. 4. Patient must have an ASA (American Society of Anesthesiologists physical status classification system) score of 1-2. 5. The absence of serious disabling diseases that would contraindicate a laparoscopy
Exclusion criteria
Exclusion criteria: 1. Extensive peritoneal and bowel carcinomatosis 2. Age more than 75 years 3. Nonepithelial ovarian cancers and borderline tumours. 4. ASA score of 3 or more 5. ECOG performance status of >= 3. 6. Laparoscopy not possible for technical reason e.g. large mass filling whole abdomen, prior multiple surgeries.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Validation of laparoscopy based model developed by Faggoti A et al (2006) to predict optimal cytoreduction in interval debulkingTimepoint: Observations noted during surgery and during hospitalisation ,Up to 5 days Post operative . | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of test performance of PIV in our population and in Faggotiâ??s populationTimepoint: Observations noted during surgery and during hospitalisation ,Up to 5 days Post operative .;Percent of patient undergoing optimum cytoreductionTimepoint: Observations noted during surgery and during hospitalisation ,Up to 5 days Post operative .;Percent of patient with complete cytoreductionTimepoint: Observations noted during surgery and during hospitalisation ,Up to 5 days Post operative .;Performance of each individual predictive score in our populationTimepoint: Observations noted during surgery and during hospitalisation ,Up to 5 days Post operative .;Test performance of laparoscopy based score to predict inoperability in terms of sensitivity, specificity, PPV and NPV in Interval cytoreduction cases .Timepoint: Observations noted during surgery and during hospitalisation ,Up to 5 days Post operative . | — |
Countries
India
Contacts
Public ContactDr Than Singh Tomar
Regional cancer centre, Thiruvananthapuram
Outcome results
None listed