Health Condition 1: null- Patients suffering from 1st time ischemic stroke suffering from post-stroke aphasia.
Conditions
Interventions
Intervention1: Group A: Comprehensive neuropsychological rehabilitation with aphasia therapy would be given along with normal clinical course of treatment by the treating doctor(neurologist). The reha
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Any Education level 2. Language: Both Hindi and/or English 3. Handedness: Right 4. Patients suffering first-time ischemic stroke diagnosed with non-fluent or fluent aphasia within a year of index event. 5. All consenting patients 6. Care giver (taking up the role of home based therapist) is available who has frequent contact with the subject (e.g. an average of 10 hours per week or more), and can accompany the subject to all clinic visits for the duration of the rehabilitation program.
Exclusion criteria
Exclusion criteria: 1. Patients suffering from more than one episode of stroke affecting language and cognition. 2. Any medical condition limiting life expectancy 3. Any major neurological disorder affecting cognition 4. Any major psychiatric disorder 5. Use of psychoactive drugs 6. Active participation in other stroke recovery trials testing experimental intervention about cognition. 7. Pregnant women. 8. Patients with any contraindication for MRI. 9. Patients having claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The impact of the Comprehensive Neuropsychological Rehabilitation on patients suffering from post-stroke aphasia would be measured through: 1. Change in the scores of Language functioning from pre to post intervention in the following domains- â?¢ Acoustic Problems â?¢ Speech and Language Problems â?¢ Simple Mathematical Problems â?¢ Perceptuo-Motor and Writing Problems â?¢ Visual and Reading Problems 2. Change in the scores from pre to post intervention of Quality of life Timepoint: The short term effectiveness of the intervention post 1 month of comprehensive neuropsychological rehabilitation with aphasia therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in scores from pre to post intervention of the following: 1. Cognitive Functioning: â?¢ Memory â?¢ Attention â?¢ Executive functioning 2. Depression 3. Correlate with changes in Neural Activations (Imaging using fMRI) Timepoint: The long term effectiveness of the intervention post 3 months of comprehensive neuropsychological rehabilitation with aphasia therapy with the use of fMRI. | — |
Countries
India
Contacts
Public ContactHarsimarpreet Kaur
All India Institute of Medical Sciences
Outcome results
None listed