Health Condition 1: null- Neurologically Diagnosed as Mild Alzheimer Disease.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: • Education: elementary education and above •Language: both Hindi & English •Medication: stabilized on cholinesterase inhibitors(Donezepil-10mg & Rivastigmine- 12mg as capsule or 10 units as patches). •Subjective memory concern reported by subject or family member •Clinical dementia rating is equal to 1.0 or 2 •Geriatric depression scale less than 6 •Caregiver availability who can accompany the subject to all clinic visits for the duration of the protocol. •Visual and auditory acuity adequate for neuropsychological testing. •Willing and able to participate in a study
Exclusion criteria
Exclusion criteria: • Any significant neurologic disease such as Parkinsonâ??s disease, multi-infarct dementia, Huntingtonâ??s disease, normal pressure hydrocephalus, brain tumour, progressive supranuclear palsy, seizure disorder, subdural hematoma, multiple sclerosis, or history of significant head trauma followed by persistent neurologic defaults or known structural brain abnormalities. • Any significant psychiatric illness or substance induced conditions. • Any systemic conditions that are known to cause dementia (hyperthyroidism, vitamin B or folic acid deficiency, niacin deficiency, hypercalcemia, neurosyphilis, HIV infection).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The impact of the intervention on the course of the disorder by measuring through - â?¢ Change in the scores of attention concentration measure â?¢ Change in the scores of memory measure â?¢ Change in the scores of verbal fluency measure â?¢ Change in the scores of QOL measure Timepoint: the short term effectiveness would be assessed after 3 months [post cognitive rehabilitation while long term effectiveness would be assessed after 6 months post cognitive rehabilitation. | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ Change in the scores of Activities of daily living measure. â?¢ Change in the social support Questionnaire Timepoint: the short term effectiveness would be assessed after 3 months post cognitive rehabilitation while long term effectiveness would be assessed after 6 months post cognitive rehabilitation. | — |
Countries
India
Contacts
All India Institute of Medical Sciences