Health Condition 1: null- Patients undergoing lower limb and lower abdominal surgeries
Conditions
Interventions
Intervention1: Ropivacaine with dexmedetomidine: Group D patients given 3 ml of Ropivacaine 0.5%
(15mg) , Frequency- single shot, Route- Intrathecal
Dexmedetomidine Dose- 1mcg/kg as loading dose , followed by 0.5mcg/kg/hr , Frequency-Continuous infusion , Route- Intravenous
Intervention2: Ropivacaine with Midazolam: Group M patients given 3 ml of
Midazolam Dose- 0.05mg/kg as loading dose , followed by 0.02mg/kg/hr , Frequency-Continuous infusion , Route- Intravenous
Control Intervention1: Ropivacaine: Ropivacaine Dose- 3cc of 0.5%(15 mg), Sin
Normal saline given intravenously
Sponsors
Dr T S Punia
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade I and II Patients undergoing lower limb and lower abdominal surgery Body mass index of 30 or less Normal coagulation profile
Exclusion criteria
Exclusion criteria: Unwilling patient, history of chronic illness, spinal abnormality, local skin infection, coagulation defects, Recent MI, Allergy to the drugs being used
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time for onset of analgesia ( highest level assessed by bilateral pin prick ) Peak sensory level reached Time taken for sensory block regression by 2 dermatomes, Time taken for motor block to recede to Bromage and Postoperative Sedation produced by the two groups, Haemodynamic profile of the two groups , Need of additional analgesic , Incidence of complications including depression, nausea, vomiting, pruritus, hypotension, bradycardia, shivering between the two groups Timepoint: Intraoperative ,Intraoperative, Postoperative, Postoperative, Intraoperative, every 5 minutes for the first 30 minutes and then every 10 minutes till the end of surgery and then at 4, 8, 12, 24 hours postoperatively, Intraoperative, Intraoperative and Postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| Time for onset of analgesia ( highest level assessed by bilateral pin prick ) Peak sensory level reached, Time taken for motor block to recede to Bromage and Postoperative Sedation produced by the two groups, Haemodynamic profile of the two groups , , Incidence of complications including depression, nausea, vomiting, pruritus, hypotension, bradycardia, shivering between the two groups Timepoint: Intraoperative,Intraoperative,Postoperative, Intraoperative ,Intraoperatively every 5 minutes for the first 30 minutes and then every 10 minutes till the end of surgery and then at 4, 8, 12, 24 hours postoperatively, Intraoperative and Postoperative | — |
Countries
India
Contacts
Public ContactDr Divya Arora
Government Medical College, Rajindra Hospital, Patiala
Outcome results
None listed