Health Condition 1: null- Patients with coronary artery disease requiring coronary angioplasty as treatment modality
Conditions
Interventions
Intervention1: Sirolimus eluting non polymer stent: Drug eluting stent ( sirolimus based polymer free stent) delivered thourgh intra arterial route, stent placed within the vessel at site of stenosis.
Sponsors
Government Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with stable coronary artery disease/ Unstable angina / NSTEMI / or recent myocardial infarction ( more than one week from the day of MI) who are being taken up for elective angioplasty
Exclusion criteria
Exclusion criteria: 1. Patients older than 80 years 2. Patients who are have developed adverse drug reactions or are allergic to aspirin, clopidogrel or statins 3. Patients with chronic renal failure 4. Patients who are likely to discontinue medications or whose compliance is questionable 5. Patients with expected survival of less than one year due to co-morbid conditions 6. Patients with severe peripheral vascular disease 7. Patients who are within one week of a myocardial infarction( STEMI) 8. Patients who refused informed consent 9. Patient who insist on pursuing treatment under alternative systems of Medicine like Ayurveda, Homeopathy, Unani, or Siddha 10. Patients with significant valvular heart disease other than Mitral valve prolapse with mild mitral regurgitation 11. Patients who require anti-coagulation for other reasons like intra -mural thrombus, atrial fibrillation, or valve replacement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite of cardiac death, Clinically driven target vessel revascularisation and MI ( both fatal and non fatal)Timepoint: The follow up period is for one year from the last recruitment. All events in this time period will be taken. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Cardiac death at the end of one year 2) MI ( fatal and non fatal ) at the end of one year 3) Non Fatal MI at the end of one year 4) Clinically Driven Target vessel revascularisation at the end of one year 5) Stroke ( both hemorrhagic and ischemic ) at the end of one year 6) All cause mortality at the end of one year 7) Non cardiac cause of death at the end of one year.Timepoint: During study period | — |
Countries
India
Contacts
Public ContactSunitha Viswanathan
Department of Cardiology, Government Medial College, Thiruvanathapuram, Kerala
Outcome results
None listed