Health Condition 1: null- WOMEN diagnosed with intrauterine foetal death after 20 weeks of pregnancy.
Conditions
Interventions
Intervention1: MIFEPRISTONE AND MISOPROSTOL: 200mg mifepristone tablet orally followed after 36-48 hrs by misoprostol,50-100µg vaginally at the interval of 6hrs for 4doses.
Control Intervention1: P
Sponsors
NRS MEDICAL COLLEGE KOLKATA
Eligibility
Inclusion criteria
Inclusion criteria: Women with period of gestation >20 weeks presenting with dead fetus as confirmed by ultrasonography without clinical evidence of active labour, bleeding per vagina, or ruptured membranes were included.
Exclusion criteria
Exclusion criteria: Women who had known allergy to mifepristone and misoprostol or had contraindications for the use of two drugs were excluded. b. Women with known previous transmural uterine incision (caeserian section, myomectomy), with grand multiparity ( > 4 ,with Haemoglobin level below 8 gm/dl or with any medical problem as renal, liver, cardiovascular diseases or coagulopathy were also excluded. c. Women who had low lying placenta as demonstrated by ultrasonography and who showed evidence of infection, who were in active labour or had bleeding or leaking per vagina were not included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| .Rate of successful delivery without additional intervention. 2. Induction to delivery intervalTimepoint: 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.additional interventions needed 2.side effects and complications. Timepoint: 1.24 hours 2.6 weeks | — |
Countries
India
Contacts
Public ContactDrPICKLU CHAUDHURI
NRS MEDICAL COLLEGE,KOLKATA
Outcome results
None listed