Health Condition 1: null- Chronic low back pain
Conditions
Interventions
Intervention1: Active Vitamin-D3 60,000 IU/ 8Weeks: Induction phase: Active vitamin D3 in a dose of 60,000 IU/week for a period of 8 weeks will be given to the enrolled subjects (having serum vitamin
Sponsors
Department of Science Technology Chandigarh Administration
Eligibility
Inclusion criteria
Inclusion criteria: Chronic low-back pain due to disc prolapse, lumbar spondylosis, and/or spinal stenosis, for at least 3 month refractory to conservative or interventional therapies, Documented low serum 25(OH)D3 levels (
Exclusion criteria
Exclusion criteria: Patient of chronic low back pain having medical conditions requiring calcium or vitamin D supplementation (i.e., osteoporosis) Diabetes, neurological disease, History of gastric ulcers or intestinal bleeding or alcohol or drug abuse. Evidence of renal disease (Se. creatinine > 1.5), liver disease (deranged LFT). Pregnant and lactating mothers and women intending pregnancy. Evidence of other causes for neuropathy and painful conditions. Epilepsy, psychiatric and substance abuse. Patients taking Vit-D supplements during the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients achieving at least 50% pain relief as compared to the baseline pain intensityTimepoint: 2 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Overall VAS 2. Improvement in MODQ from baseline 3. Decrement in rescue medication Timepoint: Baseline and 1, 2, 3, 4 and 6 months | — |
Countries
India
Contacts
Public ContactDr Babita Ghai
Post Graduate Institute of Medical Education and Research, Sector-12,Chandigarh, India-160012
Outcome results
None listed