Health Condition 1: J324- Chronic pansinusitis Health Condition 2: null- Patients with rhinosinusitis undergoing Functional endoscopic sinus surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA physical status grade I-II 2. Patients scheduled to undergo bilateral FESS involving non-fungal sinusitis under general anaesthesia (GA)
Exclusion criteria
Exclusion criteria: Uncontrolled hypertension Hepato-renal disease Hypersensitivity to opioids Associated cranio-facial anomaly Significant cardio-vascular disease Psychiatric disorders Pre-existing hyper-reactive airways disease Chronic alcoholics and/or smokers Inability to attain/sustain induced hypotension Hyperactive response to fentanyl (apnea, hypotension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Achievement and maintenance of intraoperative induced hypotensionTimepoint: From induction of anaesthesia to end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Improvement in surgical field conditions 2. Intraoperative propofol-sparing effect 3. Frequency of intra-operative specific hypotensive supplements (if any)to anaesthesia (propofol TIVA) and analgesia (fentanyl) 4. Postoperative outcome (side effects, awakening)Timepoint: From induction of anaesthesia to 24 hrs postoperatively | — |
Countries
India
Contacts
DEPARTMENT OF ANAESTHESIOLOGY PAIN AND PERIOPERATIVE MEDICINE