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A STUDY INTENDED TO FIND THE ADEQUACY OF VARIOS DOSES OF FENTANYL BEFORE ANAESTHESIA IN ACHIEVING DESIRED HYPOTENSION

PREINDUCTION FENTANYL DOSE-FINDING STUDY FOR CONTROLLED HYPOTENSION DURING FUNCTIONAL ENDOSCOPIC SINUS SURGERY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/03/004457
Enrollment
120
Registered
2014-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J324- Chronic pansinusitis Health Condition 2: null- Patients with rhinosinusitis undergoing Functional endoscopic sinus surgery

Interventions

Intervention1: 1. Group I will recieve fentanyl 2 mcg/kg : 1. Group I- Fentanyl 2mcg/kg preinduction followed by induction of anaesthesia with propofol 2.5 mg/kg body weight, atracurium 0.5mg/kg for n

Sponsors

Department of Anaesthesiology Pain Perioperative Medicine Sir Ganga Ram Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status grade I-II 2. Patients scheduled to undergo bilateral FESS involving non-fungal sinusitis under general anaesthesia (GA)

Exclusion criteria

Exclusion criteria: Uncontrolled hypertension Hepato-renal disease Hypersensitivity to opioids Associated cranio-facial anomaly Significant cardio-vascular disease Psychiatric disorders Pre-existing hyper-reactive airways disease Chronic alcoholics and/or smokers Inability to attain/sustain induced hypotension Hyperactive response to fentanyl (apnea, hypotension

Design outcomes

Primary

MeasureTime frame
Achievement and maintenance of intraoperative induced hypotensionTimepoint: From induction of anaesthesia to end of surgery

Secondary

MeasureTime frame
1. Improvement in surgical field conditions 2. Intraoperative propofol-sparing effect 3. Frequency of intra-operative specific hypotensive supplements (if any)to anaesthesia (propofol TIVA) and analgesia (fentanyl) 4. Postoperative outcome (side effects, awakening)Timepoint: From induction of anaesthesia to 24 hrs postoperatively

Countries

India

Contacts

Public ContactDR PRABHAT KUMAR CHOUDHARY

DEPARTMENT OF ANAESTHESIOLOGY PAIN AND PERIOPERATIVE MEDICINE

drprabhat_sgrh@rediffmail.com01142252513

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026