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Study to evaluate the effect of oral drug levamisol as a supportive therapy to boost the immune system to see its effect in the treatment and prevention of recurrence of warts of the genital region .

Study on the impact of oral immunomodulator in the treatment of venereal warts

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/03/004451
Enrollment
60
Registered
2014-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with genital/venereal warts

Interventions

Intervention1: Tablet levamisol 150 mg oral tablet: Intervention arm would be given tablet levamisol 150 mg on two consecutive days in a week for 12 weeks in addition to the standard treatment in a d

Sponsors

Dr RML Hospital New Delhi
Lead Sponsor
Department of Transplant ImmunologyAIIMS
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with anogenital warts who have not received any topical treatment in last 4 weeks and any systemic therapy in last 12 weeks 2. Patients who are willing to give informed consent

Exclusion criteria

Exclusion criteria: 1. Pregnant females 2. Extensive warts 3. Any topical treatment in last 4 weeks 4. Any systemic therapy in last 12 weeks 5. Giant condyloma acuminate 6. Immunocompromised patients including HIV positivity

Design outcomes

Primary

MeasureTime frame
1. Rate of the clinical improvement and the immunological parameters mentioned below. 1 The increase in Th1cytokines (IFN gamma) is likely to be associated with decreased relapse. 2. Increase in the Th2 cytokines (IL 4 and IL 10) is likely to be associated with delayed therapeutic response and /or relapse. 3 T reg parameters Timepoint: Clinical evaluation at 4 weeks 8 weeks 12 weeks 24 weeks

Secondary

MeasureTime frame
Reduction / prevention of relapseTimepoint: 24 weeks

Countries

India

Contacts

Public ContactDr H K Kar

ICMR

drmanjulasingh@rediffmail.com9868245793

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026