Hickmanline /Permacath insertion under local anaesthesia is very painful.patient remain awake during the procedure and can have postoperative recall.By giving these drugs ,we are trying to give them analgesia and amnesia for intraoperative period. so, that it will be less traumatic to patients.

To study the efficacy of DEXMEDETOMIDINE and CLONIDINE drugs for analgesic and sedation during and after the insetion of PERMACATH/HICKMANLINE in cancer patients under MONITORED ANAESTHESIA CARE.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2014/02/004400

Enrollment

160

Registered

2014-02-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- cancer patients

Interventions

Intervention1: dex: ydyyg Intervention2: DEXMEDETOMIDINE: Its an alpha 2 agonist having sedative ,anxiolytic,analgesic properties with minimal effect on respiratory rate(depression).initial loading do

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I , II ,III

Exclusion criteria

Exclusion criteria: 1 weight more than 90 kg 2 not able to understand the use of patient controlled analgesic device. 3 renal dysfunction(serum creatinine 1.5) 4 history of any liver disease 5 prolonged use of analgesics 6 patients on betablocker 7 psychiatric illness 8 chronic alcohol abuse 9 patient with heart block 10 patient who had received sedation before the start of procedure

Design outcomes

Primary

Measure	Time frame
To record pain intensity experienced intraoperatively and amount of rescue analgesia consumed in post op period.Timepoint: 8 months	—

Secondary

Measure	Time frame
1 Haemodynamic parameters intraop and post op period. 2 Adverse effect encountered in 24 hrs.Timepoint: 8 months	—

Countries

India

Contacts

Public ContactDr Rekha Bhatia

MEDANTA THE -MEDICITY

rekha.bhatia@medanta.org8745859460

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026