Health Condition 1: null- Post keratoplasty epithelial defect
Conditions
Interventions
Intervention1: Drug: Umbilical cord serum eyedrops
: 20% umbilical cord serum eye drops 6 times a day for 14 days
Control Intervention1: Autologous eyedrops: 20% eyedrops 6 times per day for 14 days
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Operated optical keratoplasty (either penetrating keratoplasty or anterior lamellar keratoplasty). 2. Epithelial defect more than 2 mm2 on first post-operative day. 3. Patients giving consent 4.Cooperative for digital photography
Exclusion criteria
Exclusion criteria: 1.Active ocular or lid infections 2.Lid abnormalities contributory to the epithelial defect 3.Severe dry eye 4.Limbal stem cell deficiency 5.Elevated IOP 6.Impending perforation 7.Pregnant and lactating women 8.Not giving consent 9.Not motivated for follow up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.time for compelete re-epithelialization of corneal graft 2. rate of re-epithelializationTimepoint: daily till re-epithelialization | — |
Secondary
| Measure | Time frame |
|---|---|
| graft clarityTimepoint: daily till re-epithelialization ;vision gainTimepoint: daily till re-epithelialization | — |
Countries
India
Contacts
Public ContactNeha Kamble
All India Institute of Medical Sciences
Outcome results
None listed