Skip to content

A study to reduce pregnancy related complications, and all cause maternal and perinatal mortality and major morbidity in Karnataka State, India

The CLIP (Community Level Interventions for Pre-Eclampsia)Cluster Randomized Controlled Trial - CLIP

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2014/01/004352
Enrollment
81200
Registered
2014-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Blood Pressure more than 160/90 mmhg or patient having high risk symptoms like blurring of vision, stroke, loss of consciousness, vaginal bleeding Health Condition 2: O141- Severe pre-eclampsia

Interventions

Intervention1: Oral Methyldopa 750mg: Methyldopa administration in the community
relative maternal hypertension on arrival at facility (defined as sBP less than 110 mmHg) Intervention2: Intramuscular MgSO4: 10g MgSO4 intramuscular loading dose (Single dose Only) Control Interventi

Sponsors

The University of British Columbia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All pregnant women permanent residents in selected clusters of Belgaum and Bagalkot district of Karnataka

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The primary outcome will be combined maternal and or perinatal outcome (either maternal, fetal or neonatal death or severe morbidity for the mother or baby)Timepoint: During Antenatal, Delivery and Postnatal 42 day followup

Secondary

MeasureTime frame
Impact of the CLIP intervention on the delays around triage and transport.Timepoint: During Antenatal, Delivery and Postnatal 42 day followup

Countries

India, Mozambique, Nigeria, Pakistan

Contacts

Public ContactDr M B Bellad

J N Medical College

mbbellad@hotmail.com09448124893

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 27, 2026