Health Condition 1: null- Respiratory distress syndrome
Conditions
Interventions
Intervention1: Nasal Intermittent positive pressure ventilation (NIPPV): NIPPV is a noninvasive mode of ventilation used in neonates. Route of administration is through binasal prongs
Duration of supp
Sponsors
KEM Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Preterm very low birth weight infants admitted to the neonatal intensive care unit with respiratory distress and chest X-ray suggestive of RDS on mechanical ventilation
Exclusion criteria
Exclusion criteria: Infants having nasopharyngeal pathology e.g. choanal atresia, cleft lip or palate, major / lethal congenital anomalies, severe intraventricular haemorrhages were excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare efficacy of NIPPV versus NCPAP as post-extubation respiratory support in infants with RDS, in terms of respiratory failure defined by respiratory acidosis, increased oxygen requirement or apnea requiring ventilatory support during first 72 hours post-endotracheal extubation. Timepoint: 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the duration of noninvasive ventilation in the two groups. 2. To compare the duration of supplementary oxygen requirement in the two groups in hours post extubation. 3. To compare the two groups in terms of rates of bronchopulmonary disease. 4. To compare the two groups in terms of mortality, duration of hospital stay, incidence of complications, duration of mechanical ventilation including non invasive support Timepoint: 1. For Bronchopulmonary dysplasia: At 36 weeks 2. Mortality: Before discharge from NICU | — |
Countries
India
Contacts
Public ContactRuchi Nanavati
KEM Hospital Mumbai
Outcome results
None listed