Health Condition 1: null- All patients with resectable periampullary carcinoma who give informed consent for the study
Conditions
Interventions
Intervention1: Blood glucose and insulin levels
Preoperative CECT abdomen: Preoperative and postoperative Blood glucose and insulin levels
Preoperative CECT abdomen and volumetry
Control Intervention1
Sponsors
AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: All patients with resectable periampullary carcinoma who give informed consent for the study
Exclusion criteria
Exclusion criteria: Patients with diabetes mellitus Patients with pancreatic carcinoma Patients with periampullary carcinoma with associated pancreatic edema, unclear border or evidence of chronic pancreatitis ASA grade III / IV ECOG III / IV Patients who decline to consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To ascertain the frequency of new-onset diabetes in non-diabetic patients after pancreaticoduodenectomy (PD) 2. To correlate reduction in volume of pancreatic parenchyma following pancreticoduodenectomy using multi-detector row computed tomography (MDCT) imaging volumetry with development of new onset diabetes.Timepoint: 1. To ascertain the frequency of new-onset diabetes in non-diabetic patients after pancreaticoduodenectomy (PD) 2. To correlate reduction in volume of pancreatic parenchyma following pancreticoduodenectomy using multi-detector row computed tomography (MDCT) imaging volumetry with development of new onset diabetes. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To correlate incidence of pancreatic fistula rate with resected pancreatic volume after PD 2. To find the frequency and correlate reduction in volume of pancreatic parenchyma with onset of exocrine deficiency after PDTimepoint: Patient data will be collected until the time of diagnosis of new onset diabetes or tumuor recurrence or death | — |
Countries
India
Contacts
Public ContactAnand Singh
AIIMS
Outcome results
None listed