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Pain relieving strategies in Fibromyalgia Patients

Effect of Transcranial Magnetic Stimulation on Pain Modulation Status in Fibromyalgia Patients - MSPM

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/12/004228
Enrollment
90
Registered
2013-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Fibromyalgia patients with chronic pain

Interventions

Intervention1: 1. Sucrose challenge test 2. Repetitive transcranial magnetic stimulation(rTMS): 1. Sucrose 25 gm/100ml orally pre and post rTMS (4 weeks)
2. Non invasive transcranial magnetic stimulation 1.0Hz for 30min/day for five consecutive days/week) for 4 weeks 3.Patient will be followed up for pain status and anxiety scores for 6 months Contr
Fibromyalgia subjects: Normal healthy female subjects and Fibromyalgia subjects with age group between 18-50 years

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult females (age 18-50 years) diagnosed with Fibromyalgia

Exclusion criteria

Exclusion criteria: a) Pregnant and lactating mothers. b) Concomitant diseases such as osteomalacia, metabolic bone diseases, hyperthyroidism, and other chronic diseases. c) When medicines such as analgesics, anti-inflammatory or psychotropic cannot be stopped for even two days. d) A history of seizures, brain trauma, brain surgery or intracranial hypertension, pace maker or other metallic implants e) Contra-indications for TMS f) Inflammation in the joints h) abnormal levels of luteinizing hormone

Design outcomes

Primary

MeasureTime frame
The decrease in LH level in response to sucrose challenge test is deranged in fibromyalgia patients The nociceptive flexion reflex/R-III and other objective methods of pain are affected by rTMSTimepoint: Outcome name:Oral sucrose challenge test, 25gm/100 ml, pre and post rTMS, Time points:5 weeks Outcome name: Determination of Pain threshold and latency, pre and post rTMS,Time points: 5 weeks—

Secondary

MeasureTime frame
Pain in fibromyalgia is mediated by opioids rTMS is effective therapy for treatment of fibromyalgiaTimepoint: Outcome name:Oral sucrose challenge test, 25gm/100 ml, pre and post rTMS, Time points:6 months, 1 year Outcome name: rTMS, 30 min/day/20 sessions, Time points:4 weeks—

Countries

India

Contacts

Public ContactDr Renu Bhatia

All India Institute of Medical Sciences, New Delhi

sumantanwar.lifescience@gmail.com01126594765

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 26, 2026