Health Condition 1: null- Type 2 diabetes mellitus with chronic kidney disease stage 3a and 3b
Conditions
Interventions
Intervention1: Metformin: Patients with CKD stage 3a i.e eGFR 59 â?? 45 ml/min/1.73m2 will receive oral Metformin at a maximum dose of 1 gm twice daily, while those with stage 3b i.e eGFR 44 - 30 ml/m
Sponsors
Dr Manish Rathi
Eligibility
Inclusion criteria
Inclusion criteria: Patients with Type 2 diabetes mellitus and CKD stage 3a and 3b whose blood sugar is not controlled with oral hypoglycemic agents other than metformin with or without insulin.
Exclusion criteria
Exclusion criteria: 1) Patients with CKD stage 4 & 5 2) Acute kidney injury 3) Congestive cardiac failure 4) Liver failure 5) Alcohol abuse 6) Hypoxemia 7) Refusal to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum lactate and Liver function testTimepoint: At baseline, then at 2 weeks and then at 4, 8 & 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Serum creatinine 2. HbA1cTimepoint: 1. At baseline and then at 4, 8, 12 weeks 2. At baseline and then at 12 weeks | — |
Countries
India
Contacts
Public ContactDr Jegan S
Post Graduate Institute of Medical Education and Research
Outcome results
None listed