Health Condition 1: null- Adult male or female subjects with primary open angle glaucoma
Conditions
Interventions
Intervention1: Forskolin eye drops 1%: Two drops three times a day for 28 days
Control Intervention1: Nil: Nil
Sponsors
Sami labs Limited
Eligibility
Inclusion criteria
Inclusion criteria: 1 Adult patients male or female having open angle glaucoma will be included in the study 2 Glaucoma with intra ocular pressure of more than 24 mm/Hg will be included. 3 No miotic or other therapy 24 hours before 4 off systemic therapy for glaucoma for at least 4 days 5 Informed consent given
Exclusion criteria
Exclusion criteria: 1 Inflammatory ophthalmic dose during the last 3 months 2 Secondary or closed angle glaucoma 3 Bronchial asthma 4 Chronic obstructive pulmonary disease 5 Uncompensated cardiac failure 6 Sinus bradycardia 7 2nd or 3rd degree AV Block 8 Concurrent drug intake for eg β blockers diamox etc 9 Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of Forskolin eye drops 1%Timepoint: Reduction in Intra ocular pressure as compared to Baseline. Tonometric readings will be recorded at 0.5,1,2,3,4,5 and 6 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety of Forskolin eye drops 1%Timepoint: Adverse Events will be assessed at all visits - Day 1, Day 7, Day 14, Day 21 and Day 28. | — |
Countries
India
Contacts
Public ContactMs Prachi Lad
ClinWorld(P)Limited
Outcome results
None listed