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EFFECTS OF PRE-LOADING OR CO-LOADING WITH CRYSTALLOID ON BLOOD PRESSURE IN TOTAL ABDOMINAL HYSTERECTOMY UNDER SPINAL ANAESTHESIA

A COMPARATIVE STUDY OF EFFECTS OF PRE-LOADING OR CO-LOADING WITH CRYSTALLOID ON BLOOD PRESSURE IN CASES OF TOTAL ABDOMINAL HYSTERECTOMY DONE UNDER SPINAL ANAESTHESIA

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/12/004185
Enrollment
154
Registered
2013-12-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- TOTAL ABDOMINAL HYSTERECTOMY DONE UNDER SPINAL ANAESTHESIA

Interventions

Intervention1: CO-LOADING: 20 ml kg-1 lactated ringer solution rapidly from the time of identification of cerebrospinal fluid while giving sub-arachnoid block, no pre-loading Control Intervention1: PR

Sponsors

B R SINGH HOSPITAL AND CENTRE FOR MEDICAL EDUCATION AND RESEARCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Weight: 40-100 kg Height: 140-180 cm ASA- I / II Absence of liver, renal, respiratory, intestinsal, cardio-vascular, CNS diseases

Exclusion criteria

Exclusion criteria: Intra-operative blood loss > 1200 ml Spinal Induced Hypotension > 50% Initial SBP ASA- III/IV Prolong surgery > 3 hours Any contra-indication to spinal anaesthesia Failure or inadequate SAB Presence of any systemic disease Patient not willing to participate

Design outcomes

Primary

MeasureTime frame
Non-invasive blood pressure (NIBP)Timepoint: Initial reading, First 15 minute: 3 minute interval, Until completion of surgery: 5 minute interval, Post-operative: two readings 5 minute apart or two readings without vasopressor 5 minute apart

Secondary

MeasureTime frame
heart rate, vasopressors dose requiredTimepoint: Initial reading, First 15 minute: 3 minute interval, Until completion of surgery: 5 minute interval, Post-operative: two readings 5 minute apart or two readings without vasopressor 5 minute apart

Countries

India

Contacts

Public ContactBARNAVA PAL

B. R. SINGH HOSPITAL AND CENTRE FOR MEDICAL EDUCATION AND RESEARCH

drsrabonibasu@gmail.com09002021527

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026