FindTrial
Sign In

Clinical trial to study the effect of two drugs, dexmedetomidine and ketamine for post surgery pain relief in spine surgery

Comparison of analgesic effect of infusion of low dose ketamine and dexmedetomidine on postoperative pain in thoracic and lumbar spine surgery - COLKD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/11/004175
Enrollment
66
Registered
2013-11-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: ketamine: ketamine and midazolam loading dose 0.25mg/kg and 10 micrograms/kg bolus respectively over 10 minutes in immediate postoperative period followed by 0.25mg/kg/hr and 10 microgr

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 11 patients undegoing elective thoracic or lumbar spine surgery

Exclusion criteria

Exclusion criteria: hypertention, coronary artery desease, cardiac arrythmia, on alpha 2 agonist, morbid obesity, planned for elective postoperative mechanical ventilation, pregnant , breast feeding, history of heart block, heart rate <60. on beta blocker

Design outcomes

Primary

MeasureTime frame
postoperative pain by recovery score, vrs score,POSTOPERATIVE RESCUE ANALGESIC REQUIREMENTTimepoint: postoperative pain by recovery score at10,20,30,40,50,60minutes of extubation , vrs score,POSTOPERATIVE RESCUE ANALGESIC REQUIREMENT at 0,2,6,12,18,24and 48 hrs—

Secondary

MeasureTime frame
DIPLOPIA, DIZINESS, PONVTimepoint: 0, 4, 8, 12, 18, 24, 48 HRS OF EXTUBATION—

Countries

India

Contacts

Public ContactDr Nidhi Panda

PGIMER Chandigarh

nidhibp@gmail.com9914209525

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026