A trial to study whether dexmedetomidine, a new anaesthetic drug added to local anaesthetic ropivacaine for blocking nerves supplying upper limb improves the quality of anaesthesia.

To evaluate the effect of dexmedetomidine added to 0.5% ropivacaine for supraclavicular brachial plexus block on the onset time, duration of sensory, motor block and analgesia. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/11/004174

Enrollment

Registered

2013-11-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- In patients undergoing upper limb orthopedic surgery

Interventions

Intervention1: dexmedetomidine-ropivacaine vs saline-ropivacaine: The study group includes addition of 0.5 ml (50 micrograms) of dexmedetomidine to ropivacaine and compared to 0.5ml of normal saline a

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: • Patients undergoing upperlimb orthopedic surgery under supraclavicular brachial plexus block and general anaesthesia. • Age more than 18 years. • ASA physical status 1&2

Exclusion criteria

Exclusion criteria: Exclusion criteria: • Patients receiving adrenoreceptor agonist or antagonist therapy; • those with a history of cardiac, respiratory, hepatic,or renal failure; • patients with head injury and known psychiatric disordes • and pregnant women were excluded.

Design outcomes

Primary

Measure	Time frame
To evaluate the effect of dexmedetomidine added to 0.5% ropivacaine for supraclavicular brachial plexus block on the onset time, duration of sensory, motor block and analgesia.Timepoint: 24 hrs	—

Secondary

Measure	Time frame
The secondary objective is to evaluate whether dexmedetomidine added to 0.5% ropivacaine for supraclavicular brachial plexus block reduces the requirements of general anaesthetics.Timepoint: 24 hrs	—

Countries

India

Contacts

Public ContactDr Indira Gurajala

Nizams Institute of Medical Sciences, Hyderabad.

indiradevraj@yahoo.co.in07729932044

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026