Health Condition 1: null- migraine Health Condition 2: G439- Migraine, unspecified
Conditions
Interventions
Intervention1: Memantine: memantine tablets, 10 mg once daily, orally for 6 months
Control Intervention1: Placebo pills: sugar pills looking like interventional drug, as tablets, given once daily,
Sponsors
SRM University
SRM University
Eligibility
Inclusion criteria
Inclusion criteria: Patients with of migraine as assessed by International Headache Society (IHS) criteria, for at least 6 months before screening patients with between 3 and 12 migraines but no more than 15 headache days Patients willing to give consent
Exclusion criteria
Exclusion criteria: Patients having headaches other than migraine, episodic tension, or sinus headaches. If headaches failed to respond to more than 2 adequate previous regimens of migraine preventive medications Medication overuse headache Pregnant/breast feeding women Severe medical illness renal insufficiency Hypersensitivity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| improvement in migraine assessed by Headache frequency and severity monitored with headache diary Timepoint: at the end of each month for 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of migraine ( MIDAS - Migraine Disability Assessment Test ) Duration ( Duration of migraine) No of days in a month requiring rescue medication Quality of life (MSQ - Migraine-Specific Quality of Life Questionnaire ) Timepoint: at the end of each month for 6 months | — |
Countries
India
Contacts
Public ContactDr S Sundar
SRM University
Outcome results
None listed