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A clinical trial of Pregabalin for prevention of catheter-related bladder discomfort

The efficacy of Pregabalin for prevention of catheter-related bladder discomfort: a prospective, randomized, placebo-controlled, double-blind study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/11/004170
Enrollment
60
Registered
2013-11-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA grade I or II patient, Non diabetic, Non hypertensive and require catheterization

Interventions

Intervention1: Pregabalin: Pregabalin is a structural analog of gamma-aminobutyric acid (GABA).Patients in this group received, orally 150 mg pregabalin one hour prior to surgery. Control Intervention

Sponsors

Apollo Hospitals Bilaspur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grade I and II, 2.non hypertensive and non diabetic 3.scheduled for surgery under general anesthesia requiring catheterization

Exclusion criteria

Exclusion criteria: 1.patients with known sensitivity to pregabalin, 2.seizure disorders, who were taking pregabalin or gabapentin, 3.history of drug or alcohol abuse, 4.history of chronic pain or daily intake of analgesics, 5.pregnant or breast-feeding females, 6.uncontrolled medical disease (diabetes mellitus and hypertension) 7.impaired kidney or liver functions and 8.psychiatric patients

Design outcomes

Primary

MeasureTime frame
To study the effect of pregabalin for prevention of catheter-related bladder discomfortTimepoint: To study the effect of pregabalin for prevention of catheter-related bladder discomfort

Secondary

MeasureTime frame
Postoperative sedation score and postoperative fentanyl requirementTimepoint: Within 6 hr after completion of surgery

Countries

India

Contacts

Public ContactDr Vinit Kumar Srivastava

Apollo Hospitals Bilaspur

drvinit75@gmail.com9755557539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 19, 2026