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Randomised controlled trial of nebulised budesonide versus oral prednisolone in acute severe asthma in children

Efficacy of inhaled corticosteroids in acute exacerbation of asthma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/11/004162
Enrollment
80
Registered
2013-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Bronchial asthma Health Condition 2: J455- Severe persistent asthma

Interventions

Intervention1: Nebulised budesonide: The study group or budesonide group received three doses of nebulised salbutamol (0.15 mg/kg) and budesonide respirator solution (800 μg) at intervals of 20 minut

Sponsors

Department of Pediatrics Institute of Child Heath Egmore Chennai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children over 4 years of age presenting with acute exacerbation of asthma to the Emergency Department Known case of asthma

Exclusion criteria

Exclusion criteria: congenital heart disease chronic lung disease X-ray and/ clinical evidence of pneumonia Higher severities of asthma e.g. life threatening Asthma

Design outcomes

Primary

MeasureTime frame
Fitness for discharge at the end of 2 hrs, based upon clinical severity scoring systemTimepoint: 1 hour—

Secondary

MeasureTime frame
Heart rate 2. Respiratory rate 3. Oxygen saturation 4. Peak expiratory flow rates (PEFR) (at 1 hr, 4 hrs) 5. Adverse effectsTimepoint: 4 hours—

Countries

India

Contacts

Public ContactArun babu

Karpaga Vinayaga Institute of Medical Sciences (CURRENT)

cs_arulparithi@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026