Health Condition 1: null- pregnant women for induction of labor
Conditions
Interventions
Intervention1: mifepristone 400 mg: Women randomized to this group will receive 400 mg of mifepristone and will be assessed after 24 and 48 hours for Bishop Score or spontaneous onset of labor. If at
Sponsors
Govt of HP
Eligibility
Inclusion criteria
Inclusion criteria: Women admitted with indications for induction of labor from gestation 37 to 42 weeks. 2. Induction can be postponed for 48 hours. 3. Bishop score 4. Singleton pregnancy. 5. Vertex presentation. 6. Maternal age > 18 years.
Exclusion criteria
Exclusion criteria: Bishop score > 6. 2. Contraindications to vaginal delivery. 3. Oligohydramnios, IUGR. 4. Any previous cesarean section or uterine surgery. 5. Gravida >= 4. 6. Multiple pregnancies. 7. Severe pre eclampsia. 9. Renal failure, adrenal insufficiency, liver failure. 10. Patient on corticosteroid treatment. 11. Blood clotting disease or on anticoagulant therapy. 12. Intrauterine fetal death. 13. Any history suggestive of drug allergy. 14. Abruptio placentae 15. Non-reassuring fetal heart rate status.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of women entering labor after use of mifepristone alone after 24 & 48 hoursTimepoint: time from induction of labor to delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ Proportion of women vaginally delivered in each group â?¢ Proportion of women with cesarean section in each group â?¢ Proportion of women with failed induction in either group â?¢ Duration of labor in women in each group â?¢ Need and amount of oxytocin required in each group â?¢ Neonatal outcomes including ; ï?? Apgar score (1 min & 5 min) ï?? Need of phototherapy (if required; duration) ï?? Intensive care admission (if required) â?? Timepoint: time from induction of labor to delivery | — |
Countries
India
Contacts
Public ContactChanderdeep Sharma
Dr RPGMC Kangra at Tanda (HP)
Outcome results
None listed