Health Condition 1: null- vitiligo
Conditions
Interventions
Intervention1: oral mini pulse of betamethasone: Group 1: to be given oral mini pulse of betamethasone 5mg on two consecutive days a week
for 6 months followed by tapering in next 4 months
Co
Sponsors
AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: Patients fulfilling all these criteria will be included in the study • Age >18yrs • Non segmental vitiligo • Involvement of >2% of body surface area • (a) Progressive disease of any duration (having >5 new lesions in last 1 month or >15 new lesions in last 3 months) Or (b) Disease onset within last one year and continuing to have new lesions
Exclusion criteria
Exclusion criteria: Patients will be excluded from the study if they have • Segmental vitiligo • Focal vitiligo • Pure mucosal vitiligo • Stable disease • Pregnancy, lactation • Concomitant infectious diseases, uncontrolled diabetes mellitus or hypertension • Active liver disease • Patients who have taken systemic corticosteroid or other immunosupressants in last two months, or that of topical in last one month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -number of new lesions compared to previous visit. -change in size of existing lesion -extent of re-pigmentation, color match -drug related side effects if any -vitiligo impact scale Timepoint: monthly in first 6 months then 2 monthly | — |
Secondary
| Measure | Time frame |
|---|---|
| drug related side effects if any -vitiligo impact scale Timepoint: monthly in first 6 mnths then 2 monthly | — |
Countries
India
Contacts
Public ContactDr Suman Patra
AIIMS
Outcome results
None listed