Health Condition 1: null- Women 18- 75 years of age with ASA 1& 2 who are listed for elective midline abdominal surgery for the treatment of primary gynaecological cancer
Conditions
Interventions
Intervention1: Rectus sheath block: local anesthetic(0.25% bupivacaine) versus placebo(saline)
Control Intervention1: One group would receive 0.25% bupivacaine versus second group which would receive
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Women 18- 75 years of age with ASA 1& 2 who are listed for elective midline abdominal surgery for the treatment of primary gynaecological cancer
Exclusion criteria
Exclusion criteria: 1.1. Refusal to consent 2. Emergency surgery 3. Conversion following Laparoscopic surgery 4. Palliative surgery 5. Surgery for recurrent disease 6. History of previous laparotomy 7. Surgery in view of suspected intra abdominal infection 8. History of hepatic, renal disease or cardio-pulmonary disease- in cases in which diclofenac or paracetomol is contraindicated 9. Patient with platelet count less than 50,000 or Patient with deranged coagulopathy INR. 1.5 10. Obesity , BMI more than 35 11. Weight less than 50 kg
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â?¢ To compare the morphine sparing effect in the two arms (Rectus sheath block Vs Placebo) at 24 and 48 hrs.Timepoint: â?¢ To compare the morphine sparing effect in the two arms (Rectus sheath block Vs Placebo) at 24 and 48 hrs. | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ To check the appropriateness of surgically placed catheter by ultrasound â?¢ To look at incidence of catheter related complications like infection, dislodgement, blockade. â?¢ To compare the average and worst pain scores at rest and at movement between the two arms. â?¢ To compare incidence of side effects like nausea, vomiting and Effect on ambulation Timepoint: End of 48 hours | — |
Countries
India
Contacts
Public ContactDr Sumitra G Bakshi
Tata Memorial Hospital
Outcome results
None listed