Health Condition 1: null- Healthy Parturients coming for LSCS under spinal anesthesia
Conditions
Interventions
Intervention1: clonidine 1µgkg-1 added to TAP block with bupivacaine: clonidine 1µgkg-1, bilaterally, added to 20ml of 0.25% bupivacaine,
given once as a single injection,in TAP block,
following LS
Sponsors
Lady Hardinge Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 100 healthy parturients (ASA physical status I and II) carrying a singleton fetus at term, scheduled to undergo elective LSCS under spinal anaesthesia, followed by a TAP block to relieve postoperative pain
Exclusion criteria
Exclusion criteria: Patients who refused spinal anaesthesia, had any contraindication to regional anaesthesia, had any major co-morbidity or if they were unable to communicate in either English or Hindi language were excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be the duration of postoperative analgesia, defined as the time (in hours) from the giving of the bilateral TAP block with clonidine 1µgkg-1 with 0.25% bupivacaine 20 ml bilaterally or 0.25% bupivacaine 20ml alone to the time to first analgesic request in the postoperative period.Timepoint: time (in hours) from the giving of the bilateral TAP block with clonidine 1µgkg-1 with 0.25% bupivacaine 20 ml bilaterally or 0.25% bupivacaine 20ml alone to the time when patient first demands analgesia in the postoperative period. | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢the total requirement of analgesics in the first 24hours postoperatively â?¢patients satisfaction and â?¢possible clonidine side effects (nausea and vomiting, sedation, dry mouth , hypotension & bradycardia)Timepoint: . after TAP block, observed every 30 minutes for the first 2 hours, then every hour for next 10 hours and thereafter every 2 hours till the patient demands first dose of analgesia. | — |
Countries
India
Contacts
Public ContactDr Ranju Singh
Lady Hardinge Medical College
Outcome results
None listed