Health Condition 1: null- Moderately preterm Appropriate for Gestational age babies(31-33 weeks)
Conditions
Interventions
Intervention1: Early BCG vaccination: Babies born between 31-33 weeks of gestation will be given BCG vaccine at birth, as against the standard practice of vaccinating after completing 34 weeks gestati
Sponsors
University College of Medical Sciences and Guru Tegh Bahadur Hospital
Eligibility
Inclusion criteria
Inclusion criteria: The study shall include preterm AGA babies 31-33 weeks residing <10 km of GTBH and can be contacted whenever required
Exclusion criteria
Exclusion criteria: Babies of mothers suffering from tuberculosis or receiving antitubercular drugs eclampsia chronic infection severe anaemia known cases HIV positive, Hepatitis B positive Babies having clinical evidence of intrauterine infection undergoing exchange transfusion receiving blood or blood products severe birth asphyxia critically ill babies septicaemia. (3) Babies with congenital anomalies and or clinical suspicion of chromosomal disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Purified protein derivative conversion by Mantoux test (induration 5-9 mm) rate at monthsTimepoint: Purified protein derivative conversion by Mantoux test (induration 5-9 mm) rate at 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| a) Four-fold rise in interferon-gamma levels in serum from baseline levels. b) BCG take up as measured by proportion of infants with local reaction and maximum transverse diameter of BCG scar. c) Complications of BCG vaccine Timepoint: 6, 10 and 14weeks 6 months | — |
Countries
India
Contacts
Public ContactDr MMA Faridi
University College of Medical Sciences and Guru Tegh Bahadur Hospital, Dilshad Garden, Delhi
Outcome results
None listed