Health Condition 1: null- Age between 1 day to 5 Year
Conditions
Interventions
Intervention1: L rhamnosus
L plantarum: Frequency: 1 X 109 CFU - Once in a day (OD)
Total duration of therapy: - 5 days
Route of administration:- Oral
Control Intervention1: Placebo: Placebo
Sponsors
Department of Biotechnology Ministry of Science and Technology Govt of India
Eligibility
Inclusion criteria
Inclusion criteria: Infants and children aged Those who would be admitted for at least 7 days
Exclusion criteria
Exclusion criteria: Prior history of probiotic intake within 6 weeks The information of prior probiotic intake will be checked from prescription slips and the drugs carried by the patients. Patients on steroids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of in vivo colonization of two ProbioticTimepoint: Assessment of in vivo colonization of two Probiotic | — |
Secondary
| Measure | Time frame |
|---|---|
| To monitor the levels of cytokines (IL-1, IL-6, IL-10 and TNF-alpha) in Stool samples of subjects, before and after intervention. To analyze the expression of Immunoglobulin receptors (IgG & IgA) on colonocytes isolated from stool before and after intervention by Flowcytometry. Timepoint: To monitor the levels of cytokines (IL-1, IL-6, IL-10 and TNF-alpha) in Stool samples of subjects, before and after intervention. To analyze the expression of Immunoglobulin receptors (IgG & IgA) on colonocytes isolated from stool before and after intervention by Flowcytometry. | — |
Countries
India
Contacts
Public ContactDr Rama Chaudhry
All India Institute of Medical Sciences
Outcome results
None listed