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A Randomized open label clinical trial to find out efficacy of scorpion anti- Venom plus prazosin combination in children of scorpion sting envenomation

Efficacy of Scorpion Antivenom plus Prazosin compared with Prazosin alone for scorpion sting envenomation in children- a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/09/004002
Enrollment
50
Registered
2013-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- scorpio sting envenomation

Interventions

Intervention1: scorpion antivenom: 30 ML intravenous route once Control Intervention1: prazosin: 30 microgram per kg per dose in children at 3 hourly interval till clearing of all autonomic syndrome 1

Sponsors

Karuppiah pandi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children < 13 yrs presenting to Department of Paediatrics casualty/ OPD with scorpion sting with features of envenomation/unknown bite with clinical features of scorpion sting envenomation

Exclusion criteria

Exclusion criteria: Refusal of consent, No systemic envenomation features

Design outcomes

Primary

MeasureTime frame
â?¢ To find out the efficacy of Scorpion antivenom plus Prazosin in children with scorpion sting envenomationTimepoint: resoluion of clnical syndrome at the end of ten hours of admission in both arm prazoisn plus scorpion nativenom and Prazosin alone

Secondary

MeasureTime frame
Total dose of prazosin required , length of hospital stay and deterortaion to higher gradesTimepoint: within 10 hours of administration of trila regimen prazosin plus scorpion antivenom

Countries

India

Contacts

Public ContactKaruppiah pandi

Jawaharlal Institute of Postgraduate Medical Education and Research

ikpandi85@gmail.com9790880239

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 8, 2026