Effect of skin preparation with chlorhexidine-alcohol versus chlorhexidine-cetrimide followed by povidone iodine before surgery on the surgical wound infection rates: a randomized controlled trial.

Effect of preoperative skin preparation with chlorhexidine-alcohol versus chlorhexidine-cetrimide followed by povidone iodine on the postoperative surgical wound infection rates: a randomised controlled trial. - RAAW

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/09/003982

Enrollment

1340

Registered

2013-09-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with gastrointestinal disorder

Interventions

Intervention1: chlorhexidine-alcohol: 3 applications of chlorhexidine-alcohol for preoperative skin preparation just before starting surgery after anesthesia Control Intervention1: Chlorhexidine cetr

Eligibility

Inclusion criteria

Inclusion criteria: All patients between 18 to 70 years of age ASA class 1 or 2 Elective gastrointestinal surgical procedures Only patients off antibiotics for at least 5 days will be considered for inclusion in the study.

Exclusion criteria

Exclusion criteria: Patients who do not consent. known allergy to study agents (chlorhexidineâ??cetrimide or povidoneâ??iodine) uncontrolled diabetes (blood glucose levels >200 mg/dl despite medical treatment) immunosuppressive medications those undergoing emergency, laparoscopic or re-operative procedures those with clean wounds / contaminated wound/dirty wounds

Design outcomes

Primary

Measure	Time frame
To compare the frequency of surgical site infection within 30 days of surgery in patients undergoing preoperative skin preparation either with three applications of chlorhexidine-alcoholversus chlorhexidine-cetrimide followed by povidone iodine on the postoperative surgical wound infection rates Timepoint: From Post operative day 1 to post op day 30	—

Secondary

Measure	Time frame
To assess the types of surgical site infection in the two groups. To compare adverse events associated with the two skin preparation protocols. Timepoint: with in 30 days of surgery	—

Countries

India

Contacts

Public ContactDr Premanand Pattanaik

AIIMS, New Delhi

peush_sahni@hotmail.com011-26593461

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026