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The use of Dexmedetomidine for providing pain relief,sedation and tolerance of Endotracheal tube postoperatively in patients retaining the endotracheal tube postoperatively.

Efficacy of Dexmedetomidine for Postoperative Endotracheal tube tolerance,analgesia and sedation -a Prospective,Randomised Double Blind ,Controlled Trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/09/003971
Enrollment
64
Registered
2013-09-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Head and Neck cancer patients undergoing surgery.

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine is a selective alpha-2 adrenergic receptor agonist that exhibits sedative, analgesic, anxiolytic, and sympatholytic effects without respiratory drive de

Sponsors

Regional Cancer Centre Thiruvananthapuram
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and ASA II in the age group 20 -70 yrs scheduled for elective Head and Neck surgery lasting longer than 2 hours who require to retain the endotracheal tube in the post operative period

Exclusion criteria

Exclusion criteria: i) Patients below 20 yrs and above 70yrs of age . ii) ASA grade more than II iii) Patient with arrythmias iv) Patient with Congestive heart failure v) Patient with Bronchial asthma vi) Patient with dementia vii) Patient with heart block viii) Pregnant patient

Design outcomes

Primary

MeasureTime frame
To study the efficacy of Dexmedetomidine for postoperative endotracheal tube tolerance,analgesia and sedation.Timepoint: The amount of intravenous morphine required,coughing and sedation in the postoperative period till extubation.

Secondary

MeasureTime frame
Haemodynamic stability, ease of management of these patients in the intensive care unit.Timepoint: Monitoring of vital signs during the postoperative period till extubation and nurses assessment.

Countries

India

Contacts

Public ContactDr Rachel Cherian Koshy

Regional Cancer Centre Thiruvananthapuram.

rachelrcc@yahoo.com04712522431

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026