Health Condition 1: null- ASA grade I or II patient, Non diabetic, Non hypertensive and require General anesthesia with intubation
Conditions
Interventions
Intervention1: Pregabalin, Placebo: Pregabalin 150 mg and placebo will be received 1 hr prior to surgery.
Intervention2: Pregabalin: Pregabalin is a structural analog of gamma-aminobutyric acid (GABA)
Sponsors
Apollo Hospitals Bilaspur
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA grade I and II, 2.non hypertensive and non diabetic 3.scheduled for surgery under general anesthesia
Exclusion criteria
Exclusion criteria: 1.patients with known sensitivity to pregabalin, 2.seizure disorders, who were taking pregabalin or gabapentin, 3.history of drug or alcohol abuse, 4.history of chronic pain or daily intake of analgesics, 5.pregnant or breast-feeding females, 6.uncontrolled medical disease (diabetes mellitus and hypertension) and 7.impaired kidney or liver functions 8.hyperkalemia 9.increased intracranial and intraocular pressure 10.psychiatric patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effect of pregabalin on succinylcholine induced fasciculation and myalgiaTimepoint: Fasciculation will be assessed just after succinylcholine administration and duration of fasciculation will be also assesed. Myalgia will be recorded after 24 h of surgical intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative sedation score and postoperative fentanyl requirementTimepoint: Within 24 hr after completion of surgery | — |
Countries
India
Contacts
Public ContactDr Vinit Kumar Srivastava
Apollo Hospitals Bilaspur, Chhattisgarh, India
Outcome results
None listed