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Effect of the drug proton pump inhibitor in a disease where the acidic content of the stomach is regurgitated to throat (Laryngo Pharyngeal reflux Disease)

Effect of Proton pump inhibitors on Laryngopharyngeal Reflux Disease â?? A Prospective study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/08/003908
Enrollment
82
Registered
2013-08-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Laryngo Pharyngeal Reflux

Interventions

Intervention1: Pantoprazole sodium 40 mg: Tablet Pantoprazole sodium 40 mg BD for 6 weeks Control Intervention1: Pre treatment sample group: Pre treatment sample group of the same study group act as c

Sponsors

Sree Mookambika Institute of Medical Science
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a. Patients with symptoms suggestive of laryngopharyngeal reflux disease with a reflux finding score of more than 7 as per laryngeal endoscopic examination. b. Patients who are between the age group of 18 and 80.

Exclusion criteria

Exclusion criteria: a. Those who were taking proton pump inhibitors for the past one month b. Patients who are hypersensitive to proton pump inhibitors c. Those who are on any regular drugs d. Pregnant women e. Those who have not given consent f. Patients below 18 years of age g. Patients above 80 years of age h. Patients with other co-existing laryngeal pathology

Design outcomes

Primary

MeasureTime frame
Reduction in Laryngeal reflux symptom indexTimepoint: 6 weeks

Secondary

MeasureTime frame
Reduction in Laryngeal reflux finding scoreTimepoint: 6 weeks

Countries

India

Contacts

Public ContactDr H S Sabari Nath

Sree Mookambika Institute of Medical Science

drgkumar_1952@yahoo.co.in9447073194

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026