Health Condition 1: null- Intrauterine adhesions,Oligomenorrhea,Infertility
Conditions
Interventions
Intervention1: AUTOLOGOUS HAEMOPOIETIC STEM CELLS: BONE MARROW MONONUCLEAR CELL SEPARATION
1. Bone Marrow (BM) Aspiration:
Bone marrow (average 40-50 ml) will be aspirated from iliac crest/sternum u
The harvested mononuclear cells will evaluated for:
1. Viability test: Trypan blue dye exclusion test will be done to know the percentage of live cells.
2. Cell morphology: MNC will be stained with
Intervention2: AUTOLOGOUS HAEMOPOIETIC STEM CELL: 1. Bone Marrow (BM) Aspiration:
Bone marrow (average 40-50 ml) will be aspirated from iliac crest/sternum using disposable bone marrow aspiration nee
Sponsors
All India Institute of Medical Sciences AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1Women in reproductive age group with primary or secondary infertility due to severe Ashermans Syndrome, with menstrual irregularities. 2Hypomenorrhoea, oligomenorrhoea or amenorrhoea 3 In whom the available treatment options that is hysteroscopic adhesiolysis and followed by estrogen stimulation have failed. 4Women willing to participate in the study.
Exclusion criteria
Exclusion criteria: Women more than 40 years of age are not included in the study. ?Patients with active endometrial tuberculosis. ?Patients with chronic debilitating diseases and or hematopoietic diseases affecting the bone marrow. ?Women not willing to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Attaining menstruation 2.Gain in Endometrial Thickness 3.Conception Timepoint: NOT APPLICABLE | — |
Secondary
| Measure | Time frame |
|---|---|
| Not ApplicableTimepoint: Not Applicable | — |
Countries
India
Contacts
Public ContactDR NEETA SINGH
AIIMS
Outcome results
None listed