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Does copper, ceruloplasmin, total antioxidant capacity, iron and total iron binding capacity levels change in patients with alcoholic liver disease?

A CORRELATIVE STUDY OF COPPER, CERULOPLASMIN, TOTAL ANTIOXIDANT CAPACITY, IRON AND TOTAL IRON BINDING CAPACITY IN ALCOHOLIC LIVER DISEASE AND HEALTHY CONTROLS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2013/08/003887
Enrollment
80
Registered
2013-08-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- alcoholic liver disease

Interventions

Intervention1: no drugs/ intervention used. serum parameters were determined: copper, ceruloplasmin, total antioxidant capacity, iron and total iron binding capacity were determined in cases

Sponsors

Father Muller Medical college hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 50 male patients diagnosed with alcoholic liver disease will be recruited randomly for the study over a period of 1 year. Diagnosis, medical history, relevant clinical findings and liver function tests will be obtained from the clinical case files. Alcohol consumption related data will be obtained by using AUDIT which is a screening questionnaire for detailed alcohol use history. Controls include thirty age-matched normal, apparently healthy males. CAGE questionnaire will be administered to volunteers to exclude those with problem drinking.

Exclusion criteria

Exclusion criteria: I. Patients younger than 30 yrs and older than 80 yrs II. Patients with renal disease, smokers, tobacco chewers, on exogenous steroid or suffering from any other systemic illness (infections, malignancies, respiratory diseases) will be excluded.

Design outcomes

Primary

MeasureTime frame
serum parameters yet to be changedTimepoint: serum parameters yet to be changed

Secondary

MeasureTime frame
not applicableTimepoint: not applicable

Countries

India

Contacts

Public ContactDr Malathi M

Father Muller Medical College, Mangalore

jacob_jeena@hotmail.com08971271339

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026