A clinical trial to study the effects of two drugs, Fentanyl and Butorphanol in combination with another drug Propofol for general anaesthesia using a device called Laryngeal mask airway.

Comparative evaluation of Fentanyl versus Butorphanol during induction with Propofol on LMA insertion conditions

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/08/003881

Enrollment

Registered

2013-08-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Classical Laryngeal Mask Airway insertion condition on American Society of Anaesthesiologists Physical Status I and II patients who require requires general anaesthesia for short surgical procedures

Interventions

Intervention1: Intervention agent: Intravenous Butorphanol - 20 microgram/kilogram single dose: Intervention agent: Butorphanol. dose - 20 microgram/kilogram, frequency - single dose, duration - once

Eligibility

Inclusion criteria

Inclusion criteria: Adult males or females of age group 18 to 55 years who comes under the American Society of Anaesthesiologists (ASA) Physical Status I and II for short surgical procedures who need LMA for maintaining general anaesthesia.

Exclusion criteria

Exclusion criteria: Patients of the American Society of Anaesthesiologists (ASA) Physical Status III and IV, those who suffer from pharyngeal pathology, low pulmonary compliance or history of allergy to Propofol, Butorphanol and Fentanyl.

Design outcomes

Primary

Measure	Time frame
Jaw relaxation according to Youngâ??s criteriaTimepoint: 60 seconds following the studied drug and Propofol is administered	—

Secondary

Measure	Time frame
Overall LMA insertion condition according to modified Scheme of Lund and StovenerTimepoint: 60 seconds following the studied drug and Propofol is administered	—

Countries

India

Contacts

Public ContactDr Sobha S

Government Medical College, Thiruvananthapuram

sobhathambu@yahoo.co.in9497640396

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026