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Epidemiological, Clinical and Histopathological prognostic factors in Advanced Oral Squamous Cell Carcinoma treated with Surgery followed by Radiotherapy: A Retrospective Observational study

Epidemiological, Clinical and Histopathological prognostic factors in Advanced Oral Squamous Cell Carcinoma treated with Surgery followed by Radiotherapy: A Retrospective Observational study - OSCC

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2013/07/003855
Enrollment
100
Registered
2013-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- PATIENTS OF ADVANCED ORAL SQUAMOUS CELL CARCINOMA

Interventions

None listed

Sponsors

MAX SUPERSPECIALTY HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: . Patients of any age. . Sex: both males and females . Histological biopsy confirming Squamous Cell Carcinoma of the Oral cavity (tongue, gingiva, buccal mucosa, floor of mouth, palate, and retro molar region) . Clinical stage III/IVA (T1-2, N1-2, M0 or T3-4, N0-2, M0, AJCC 2006) with resectable lesions. • Adequate hematologic function: white blood cell >3,000/mm3, hemoglobin >8g/L, platelet count >80,000/mm3.

Exclusion criteria

Exclusion criteria: . Patients with distant metastatic disease and other cancers • Previous radiotherapy, surgery or chemotherapy done other than Max • Other previous malignancies within last 5 years • Another histological type of tumour or a tumour not involving the oral cavity, • Recurrent tumour after previous treatment. • Patients with inadequate follow-up • Patients who have undergone for initial RT

Design outcomes

Primary

MeasureTime frame
â?¢ To determine the stage and size of the tumor â?¢ To assess the kind of the surgical technique and the technique of the radiation used â?¢ To determine the tumor histology grade depth of invasion presence of LVI and PNI bone invasion tumour differentiation types of surgical margins on the specimen and resection margin â?¢ To determine the regional node size site and number of lymph nodes invaded lymph node sectors invaded presence of extracapsular extention and distant metastasis Timepoint: from Feb 2009 to Sep 2012

Secondary

MeasureTime frame
â?¢ To evaluate the early effect of age gender tobacco chewing smoking alcohol consumption dental hygiene and presence of the comorbidities on the prognosis of the diseaseTimepoint: from Feb 2009 to Sep 2012

Countries

India

Contacts

Public ContactABIDA PARVEEN

MAX SUPERSPECIALTY HOSPITAL

harit.chaturvedi@maxhealthcare.com9810008781

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026