Health Condition 1: null- A patient of pituitary macroadenoma usually suffers with endocrinological problems or with problems associated with mass effect of tumor on adjacent structures.
Conditions
Interventions
Intervention1: MRI: MRI based neuronavigation
Control Intervention1: Fluroscopy: Real time fluroscopy guidance
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Pituitary macroadenoma 2.Size - From 1 cm to 4 cm 3.Proper consent available and willing for regular follow up till 3 months
Exclusion criteria
Exclusion criteria: 1.Age greater than or equal to 18 years 2.Microadenoma 3.Tumor size more than 4 cm in any dimension. 4.Involving two compartments or more. 5.Tumor reaching within 6mm of foramen of monro 6.Absolute Contraindication for trans-sphenoidal surgery â?? Acute Sphenoid sinusitis 7.Re-do surgery 8.Adjuvant Radiotherapy/ Gamma knife radiosurgery 9.Radiological or intra-operative evidence of extensive bone, duramater and sinuses involvement 10.Radiological evidence of > 50% encasement of ICA circumference 11.Histopathology report other than those categorised as pituitary adenomas
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of tumor removed.Timepoint: Immediate post operative period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Residual /recurrent tumor 2. Assess and compare short term outcome in the two armsTimepoint: Three months. | — |
Countries
India
Contacts
Public ContactDr Vivek Tandon
All India Institute of Medical Sciences
Outcome results
None listed