Health Condition 1: null- diabetes
Conditions
Interventions
Intervention1: Tablet Metformin 500 mg per orally twice daily: Tablet Metformin 500 mg per orally twice daily for 3 months
Control Intervention1: Metformin: Tablet Metformin 500 mg per orally twice da
Sponsors
nil
Eligibility
Inclusion criteria
Inclusion criteria: 1)Individuals should have type 2 Diabetes Mellitus 2)Duration of disease less than 5 years 3)Body mass index less than 23 kg per meter square 4)Glycosylated Hemoglobin more than 7% 5)Fasting plasma glucose more than 140 mg/dl 6)Post prandial sugar more than 200 mg/dl
Exclusion criteria
Exclusion criteria: 1)Age less than 18 years and more than 65 years 2)Duration of Diabetes Mellitus more than 5 years 3)Body mass index more than 23 kg per meter square 4)Glycosylated Hemoglobin less than 7% and more than 10 % 5)Fasting plasma glucose less than 140 and more than 200 mg/dl 6)Post prandial sugar less than 200 mg/dl and more than 300 mg/dl 7)Serum creatinine more than 1.4 mg/dl in females and more than 1.5 mg/dl in males or urine albumin more than 300 mg/ 24 hours 8)Patients with acute or chronic liver disease 9)Patients with secondary cause for diabetes 10)Patients who are on drugs which can affects the glucose homeostasis 11)Pregnant and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in fasting plasma glucose, 2 hour plasma glucose after 75 gm oral glucose glucose and HbA1cTimepoint: at baseline and after 3 months of treatment with Metformin | — |
Secondary
| Measure | Time frame |
|---|---|
| change in fasting serum lipid profile and CRPTimepoint: 0 and 3 months | — |
Countries
India
Contacts
Public ContactDR RAMESH GOMEZ
Sanjay Gandhi Post Graduate Institute of Medical Sciences
Outcome results
None listed