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To evaluate skin hydration and tolerance, after application, of 3 test product creams containing Dexpanthenol 5% and Allantoin 0.5% in 3 different base formulations, on inner forearms , over duration of 24 hours.

Evaluation of the efficacy (skin hydration) and safety, after application, of 3 test product creams containing Dexpanthenol 5% and Allantoin 0.5% in 3 different base formulations, on inner forearms , over duration of 24 hours.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/06/003765
Enrollment
12
Registered
2013-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Dexpanthenol 5% and Allantoin 0.5% in base formulation 1: 0.020 g of the test product will be applied on test site by massaging for 30 seconds using a finger-stall. Control Intervention

Sponsors

Dr Reddys Laboratories Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Voluntary women/men between 18-45 years. b) Having signed a Consent Form after the trial has been explained orally and in writing, of all information concerning the study procedures and study objectives. c) Dry skin type (Clinical evaluation followed by MoistureMeter SC Readings which should be d) Presenting healthy skin on test sites. e) Cooperating, informed of the need and duration of the examinations

Exclusion criteria

Exclusion criteria: a) Menopausal/Pregnant women by taking history. b) Allergic to any cosmetic product. c) A volunteer who the Investigator feels will not be compliant with trial requirements. d) Any type of skin disorder which investigator feels will interfere with the study e) Subjects on any medical treatment either systemic or topical which may interfere with the performance of the study treatment (presently or in the past 1 month). E.g. topical steroids. f) Chronic illness which may influence the skin sensitivity (skin problems like atopic dermatitis, psoriasis, eczema or diseases like hypothyroidism, anemia, hormonal problems or patients on anti cholesterol drugs, etc) g) Any cutaneous disease which would predispose to dry skin (confirmed by prior history). h) Any cutaneous conditions on test site (scars, moles, papules etc). i) Women having their menstrual cycle during the study. j) Subject in an exclusion period or already participating in another similar cosmetic or therapeutic trial as identified during screening on visit 1 (V1).

Design outcomes

Primary

MeasureTime frame
Hydration measurements using the instrument Moisture Meter SC Compact. ï?? Transepidermal water Loss measurements using the instrument VapometerTimepoint: 0 hour, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours and 24 hours—

Secondary

MeasureTime frame
Clinical examination of skin for local reactions, if anyTimepoint: over duration of 24 hours—

Countries

India

Contacts

Public ContactMr Srimannarayana
rsjdr@rediffmail.com66758851

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026