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EFFECT OF PREOPERATIVE AND POSTOPERATIVE SYNBIOTICS(PREBIOTICS AND PROBIOTICS)ON INFECTIVE COMPLICATIONS FOLLOWING LIVER AND PANCREATIC SURGERY

IMPACT OF PERIOPERATIVE ENTERAL SYNBIOTICS IN HEPATIC & PANCREATIC SURGERY: A SINGLE BLIND PROSPECTIVE RANDOMIZED CONTROL TRIAL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/06/003737
Enrollment
120
Registered
2013-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Hepatic Surgery and Pancreatic Surgery

Interventions

Intervention1: Synbiotics: Specific synbiotic composition of prebiotics and probiotics Streptococcus faecalis T-110 â?? 60 million, Clostridium butyricum TO-A â?? 4 million, Bacillus mesentericus TO

Sponsors

Govt Stanley Medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults between 18 and 75 years old in good general status (Karnofsky performance score >80) All major pancreatic resection surgeries included in the study (Whipple procedure, Distal pancreatectomy, Frey procedure). All Hepatic resections are included in the study.

Exclusion criteria

Exclusion criteria: Renal insufficiency (creatinine > 1.1) Intestinal obstruction Emergency surgery Cerebral disorders with danger of aspiration Contraindications for enteral nutrition

Design outcomes

Primary

MeasureTime frame
occurrence of postoperative bacterial infectionTimepoint: within first 30 postoperative days—

Secondary

MeasureTime frame
Mortality First bowel movement Days in intensive care unit Length of hospital stay Duration of antibiotic therapy.Timepoint: NA—

Countries

India

Contacts

Public ContactAshwin Rammohan

Govt. Stanley Medical College Hospital

gastrosurgeon@gmail.com00919884173583

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 10, 2026