Health Condition 1: null- Acute inflammatory episodes of knee joint osteoarthritis
Conditions
Interventions
Intervention1: Individualized homeopathic
medicines in appropriate doses: Single individualized
homeopathic remedy orally in
centesimal potencies, as appropriate. Each
dose in centesimal potency consi
Sponsors
Mahesh Bhattacharyya Homeopathic Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: a)Age between 18-86 years [19] b)Both sexes c)Clinically diagnosed cases of knee osteoarthritis, as per American College of Rheumatology criteria, suffering from acute inflammatory episodes of the condition; with or without involvement of other joint(s); with or without imaging and/or other investigatory evidences d)Patients already undergoing regular oral/topical analgesics/NSAIDs therapy for acute inflammatory episodes of osteoarthritis, provided the medications are stopped completely; however, patients on life-saving conventional drug therapies, e.g. anti-diabetics, anti-hypertensives, thyroid drugs etc. for co-morbidities under control, will be continued.
Exclusion criteria
Exclusion criteria: a)Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( > 12°); evidenced by imaging or other evidences and requiring surgical intervention b)Non-ambulant patients c)Self-reported joint disorders (e.g. inflammatory joint disease, specific arthropathy, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs) other than OA d)IA corticosteroid injections within 2 weeks prior to study entry [19] e)Uncontrolled, unevaluated and/or complicated diabetes mellitus, hypertension, and other co-morbidities f)Cases with other systemic unevaluated or uncontrolled diseases like cardiovascular, renal, gastro-intestinal, endocrinal, gynecological diseases etc. or systemic infections affecting quality of life or on other treatment therapies g)Psychiatric illness h)Patients with any vital organ failure i)Recent significant knee surgery within last 6 months j)Cases with transplanted knees k)History of homeopathic treatment for any chronic disease within last 6 months l)Self-reported immune-compromised states m)Alcohol/drug addiction or dependence n)Inability to comply with the study protocol o)If any exclusion criteria develop during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC Visual Analogue Scales of 100 mm for pain, stiffness, and limitation of physical function; two additional 0-100 mm VASs measuring general wellbeing and quality of sleep; OARSI - OMERACT osteoarthritis pain measure; and safety of homeopathic treatmentTimepoint: 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 50 foot walk test; Knee injury and osteoarthritis outcome score; need for concomitant therapy; Adverse Events/Serious Adverse Events; withdrawal due to AE/SAE/lack of efficiency; number of deathsTimepoint: 7 days | — |
Countries
India
Contacts
Public ContactShubhamoy Ghosh
Outcome results
None listed