comparison of 2 schedules of chemotherapy in concurrent chemoradiation in head and neck cancer

comparison of concurrent chemoradiation with weekly versus 3 weekly cisplatin in locally advanced head and neck squamous cell carcinoma

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/05/003703

Enrollment

100

Registered

2013-05-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Locally advanced squamous cell carcinoma of head and neck region.

Interventions

Intervention1: Concurrent chemoradiation.: Conventional radiotherapy 66Gy in 33 fractions over 6.5 weeks along with cisplatin(40mg/m2) weekly, for locally advanced squamous cell carcinoma of the head

Eligibility

Inclusion criteria

Inclusion criteria: 1)ECOG performance status 0 and 1 2)SCC of oral cavity,oropharynx,hypopharynx and larynx

Exclusion criteria

Exclusion criteria: 1)patients with cartilage and bone involvement 2)patients with distant metastasis 3)age >70years

Design outcomes

Primary

Measure	Time frame
locoregional controlTimepoint: 2 months after completion of treatment	—

Secondary

Measure	Time frame
1)Acute and chronic toxicity 2)Quality of lifeTimepoint: During treatment and follow up	—

Countries

India

Contacts

Public ContactDr Rejnish Kumar R

lekhamnair28@gmail.com9447072333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 27, 2026