Skip to content

Comparison of two diagnostic tests, EEG and Neuroimaging) in the evaluation of children with seizures

Neuroimaging versus EEG as the Initial Investigation for First Afebrile Seizure in Neurologically normal children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2013/05/003673
Enrollment
170
Registered
2013-05-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Neurologically Normal Children With First Episode of Afebrile Seizures

Interventions

Intervention1: Neuroimaging: The standard MRI sequence employed for evaluation shall include sagittal and axial T1, axial spin-echo proton density and T2, coronal T2, and high-resolution coronal T2 of

Sponsors

ESI Hospital and Postgraduate Institute of Medical Sciences Research ESIPGSMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ? Presenting to the Pediatric department of ESI hospital with first episode of unprovoked, afebrile generalized tonic clonic or tonic, or partial seizures (or suspected seizures) ? Neurologically normal children No development delay on history and no evidence of Neuroregression Normal head circumference No abnormal neurological findings Normal fundus examination

Exclusion criteria

Exclusion criteria: 1. Status epilepticus; 2. Seizures associated with o an acute CNS infection (e.g., meningitis, encephalitis), o head injury, or o systemic illness known to be associated with seizures (e.g., Shigella encephalopathy, SSPE); 3. Admitted for a suspicion of seizure but discharged with an alternated diagnosis e.g., breath-holding spell, pseudoseizure; 4. Recognizable dysmorphism or neurocutaneous syndrome; and 5. Persistent alteration of mental status or failure to return to baseline after the seizure

Design outcomes

Primary

MeasureTime frame
?Proportion of investigations having clinically relevant information (CRI) in children evaluated initially with neuroimaging OR EEG.Timepoint: Four weeks

Secondary

MeasureTime frame
? Etiologies of first afebrile seizure in children ? Time taken to schedule the investigations in children with FAS ? Number of hospital visits made for investigative workup of FAS ? Adverse events associated with investigations in children with FAS Timepoint: Four weeks

Countries

India

Contacts

Public ContactDr Jyoti Bagla

ESIPGSMR

jyotibagla@yahoo.co.in91-9711719117

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026