ALTERED FRACTIONATED RADIOTHERAPY SCHEDULES IN ORAL CAVITY CANCERS

Comparison Between Conventional and Accelerated Hypofractionation Radiotherapy in Oral Cavity Cancers - CCART

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2013/05/003650

Enrollment

100

Registered

2013-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: GROUB B: EXPERIMENTAL ARM, ALTERED FRACTIONATED RADIOTHERAPY IN ORAL CAVITY CANCERS: 52.50 Gy in 15 fractions over 3 weeks as per MANCHESTER Schedule Control Intervention1: GROUP A: CON

Eligibility

Inclusion criteria

Inclusion criteria: 1.Histologically proven squamous cell carcinoma of oral cavity 2.T1 to T4a(skin) N0 N1 disease intended to be treated with radical radiotherapy 3.ECOG Performance Status 0,1 4.Patients willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Age 70 yrs. 2.Non squamous cell carcinoma of head and neck region 3.N2 & above 4.Field size > 81 sq cm 5.Prior chemotherapy & radiotherapy 6.Metastatic disease 7.Pregnant women 8.Mentally unfit to give consent

Design outcomes

Primary

Measure	Time frame
1.Response Rate 2.Toxicity 3.QOLTimepoint: 5 TO 6 MONTHS AFTER COMPLETION OF TREATMENT	—

Secondary

Measure	Time frame
1.Disease free survival 2.Overall survival Timepoint: 5 TO 6 MONTHS AFTER COMPLETION OF TREATMENT	—

Countries

India

Contacts

Public ContactDR PAUL GEORGE

REGIONAL CANCER CENTRE TRIVANDRUM

paulpampz04@gmail.com8547012004

Outcome results